What is the Jeffrey Model Foundation?
About Jeffrey Modell Foundation JMF is a global nonprofit organization dedicated to early diagnosis, meaningful treatments and, ultimately, cures through research, physician education, public awareness, advocacy, patient support, and newborn screening.
Who is Jeffrey Modell?
Vicki and Fred Modell established the Jeffrey Modell Foundation, a 501(c)3 nonprofit organization, in 1987, in memory of their son Jeffrey, who died at the age of fifteen from complications of Primary Immunodeficiency – a genetic condition that is chronic, serious, and often fatal.
What is primary immunodeficiency syndrome?
Primary immune deficiency diseases (PIDDs) are rare, genetic disorders that impair the immune system. Without a functional immune response, people with PIDDs may be subject to chronic, debilitating infections, such as Epstein-Barr virus (EBV), which can increase the risk of developing cancer. Some PIDDs can be fatal.
Are the warning signs of primary immunodeficiency defined?
Signs and symptoms of primary immunodeficiency can include: Frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections. Inflammation and infection of internal organs. Blood disorders, such as low platelet count or anemia.
What are immunodeficiency disorders?
Immunodeficiency disorders may affect any part of the immune system. Most often, these conditions occur when special white blood cells called T or B lymphocytes (or both) do not function normally or your body does not produce enough antibodies.
What is the most common primary immune deficiency disorder?
In the United States, common variable immunodeficiency is the most frequently diagnosed primary immunodeficiency.
Can you grow out of hypogammaglobulinemia?
Most children born with transient hypogammaglobulinemia of infancy will grow out of it between the ages of 2 and 5. Other types of hypogammaglobulinemia are lifelong conditions. The risk of infection can be reduced by different treatments, depending on the type and cause of hypogammaglobulinemia.
Does low IgG make you tired?
Purpose: Individuals with immunoglobulin G deficiency (IgGsd) often complain of fatigue.