How often do giant cell tumors come back?
For most cases, the postoperative recurrence could be observed within 24 months after the surgery. Depending on the type of surgical procedure and local presentation of the tumor, the recurrence rate of GCTB could range from 2.5% to 45% [5], [6].
Can you have multiple giant cell tumors?
In rare cases, a patient can have multiple giant cell tumors in different bones, a condition called multi-centric giant cell tumor of bone. Most giant cell tumors occur in patients between 20 and 40 years of age. They do not typically occur in children or in adults older than 65 years of age.
How common is giant cell tumor of tendon sheath?
Giant cell tumor of tendon sheath (GCTTS) is the second most common tumor of the hand, typically presenting in the third to fourth decade of life (1). Also known as localized nodular tenosynovitis, GCTTS is characterized by diffuse presence of multinucleated giant cells and proliferation of synovial-like cells (2).
Is giant cell tumor of tendon sheath cancer?
A tendon sheath is a layer membrane that covers a tendon. Tendons are fibrous tissue that connects muscle to bone. These tumors cause the affected synovium, bursae or tendon sheaths to thicken and overgrow. They are benign, which means they are not cancerous and do not spread to other areas of the body (metastasize).
Do giant cell tumors come back?
Tumors that can’t be removed surgically can often be controlled and sometimes destroyed with radiation therapy. Giant cell tumors can come back. Follow-up with your healthcare provider may be required for several years.
What is the prognosis of giant cell tumor?
A review of the world literature1,2,6,7,39,40 revealed an 80% to 85% survival rate in patients with pulmonary metastases from giant cell tumor of the bone. In fact, spontaneous regression of pulmonary lesions has been reported in the literature.
Can giant cell tumor come back?
Can a giant cell tumors return?
Is giant cell tumor life threatening?
Giant cell tumors are rarely life-threatening. But they can damage your bones and tissues.
Can giant cell tumor become malignant?
Background: Primary and recurrent giant cell tumor of bone is typically benign; however, rarely giant cell tumor of bone can undergo malignant transformation.
Can giant cell tumors metastasize?
Giant cell tumors of bone are sometimes locally aggressive and may metastasize, although uncommonly. We attempted to identify associations of clinical and histopathologic parameters with metastasis, the long-term outcome with metastases, and the best treatment.