What is a cardioprotective medication?

What is a cardioprotective medication?

Summary. Cardioprotective drugs are important in the treatment of patients at risk for or with documented cardiovascular disease (CVD). Beta-blockers are indicated for a wide range of patients with cardiac pathologies, including acute coronary syndrome, stable coronary artery disease, heart failure, and arrhythmias.

Which diabetes medications are cardioprotective?

The American Diabetes Association and European Association for the Study of Diabetes consensus recommendations identify metformin as first-line therapy, after which the addition of cardioprotective therapy with a GLP-1RA or SGLT2i can be considered [50].

What is cardioprotective effect?

Cardioprotection includes “all mechanisms. and means that contribute to the preservation of. the heart by reducing or even preventing myocar- dial damage”.

How is bisoprolol cardioprotective?

Bisoprolol conferred cardioprotective effects by improving postischemic cardiac function, decreasing infarct size, reducing apoptotic index, diminishing serum creatine kinase and lactate dehydrogenase levels, suppressing TNF-α and IL-6 secretion, inhibiting UPR signal pathways and downregulating caspase-12 and caspase- …

What cholesterol is cardioprotective?

Often referred to as ‘good’ cholesterol, high levels of HDL cholesterol have been associated with reduced cardiovascular risk in observational studies. The proposed cardioprotective mechanisms of HDL include its role in reverse cholesterol transport and in modulating inflammation.

Which dietary fats are cardioprotective?

Flaxseed, canola, and soybean oil provide alpha-linolenic acid, the plant-derived omega-3. One teaspoon of oil provides ~40 kcal; 1 tablespoon of spread provides ~70 kcal.

What is the best medicine to lower A1c?

While results showed liraglutide and insulin were the most (and similarly) effective in keeping A1C levels less than 7%, glimepiride had a smaller effect and sitagliptin showed the lowest effect, resulting in the highest frequency of developing A1C levels persistently greater than 7%.

Is insulin a cardioprotective?

Conclusions. Insulin exerts cardioprotective effects via glucose-dependent and -independent mechanisms, including aversion of glucose toxicity; positive inotropy; the interrelated modulation of oxidative stress, inflammation, and apoptosis; and regulation of blood flow.

Does Resveratrol help the heart?

Some research shows that resveratrol could be linked to a lower risk of inflammation and blood clotting, which can lower the risk of heart disease. But other studies found no benefits from resveratrol in preventing heart disease.

Is there an alternative to bisoprolol?

Common beta blockers include: atenolol (brand names include Tenormin) bisoprolol (brand names include Cardicor, Emcor) carvedilol. esmolol.

What HDL level is cardioprotective?

Low HDL levels (less than 50 mg/dl) seem to be a stronger risk indicator for women than men. HDL levels of 60mg/dl or higher are considered “cardio protective” because they lower the risk of heart disease.

Are high HDL levels cardioprotective?

What macronutrient is easiest for the body to digest?

Carbohydrates are the quickest, and fats are the slowest. Carbohydrates, proteins, and fats are digested in the intestine, where they are broken down into their basic units: Carbohydrates into sugars.

What are the best heart health supplements?

8 heart health supplements to take – and one to avoid

• Multivitamin & mineral. Vitamins and minerals taken in appropriate doses may aid in lowering heart disease risk.
• Coenzyme Q10 (Co Q10) Coenzyme Q10 (CoQ10) is a substance similar to a vitamin.
• Fiber.
• Omega-3 fatty acids.
• Magnesium.
• L-Carnitine.
• Green tea.
• Garlic.

Are sulfonylureas cardioprotective?

Background—The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect nonpancreatic KATP channels less than does Glib.

How are SGLT2 inhibitors cardioprotective?

Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis. Protein Cell.