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How does dual antiplatelet therapy work?

How does dual antiplatelet therapy work?

Dual antiplatelet therapy (also called DAPT) is a treatment to help stop harmful blood clots from forming. This involves taking 2 types of antiplatelet medicines. One of these medicines is usually ASA (aspirin) and the other is a special type of medicine called a P2Y12 inhibitor.

Can doxycycline be given via PEG tube?

The contents of some soft gelatin capsules may be withdrawn and administered via tube eg nifedipine. Doxycycline capsules contain an irritant salt and should not be opened to facilitate administration. Dispersible tablets should be used instead.

Can you crush calcitriol?

The capsule of this medication should not be opened, crushed or chewed.

Why is dual antiplatelet therapy recommended?

1 Dual antiplatelet therapy (DAPT) provides more intense platelet inhibition than single antiplatelet therapy resulting in incremental reductions in the risk of thrombotic events after percutaneous coronary intervention (PCI) or ACS, but it has been associated with an increased risk of major bleeding.

When do you use dual antiplatelets?

Dual antiplatelet therapy with aspirin and a P2Y12 receptor antagonist is standard of care in acute coronary syndrome and is recommended for a period of 12 months regardless of invasive revascularization.

How many times a day should you take doxycycline?

The usual dose is 100mg to 200mg, taken once or twice a day. You might take a lower dose, such as 40mg once a day or 20mg twice a day, for rosacea or gum infections. Children younger than 12 years old may need to take a lower dose than adults.

Can calcitriol damage kidneys?

Inactivating mutations in this gene cause idiopathic infantile hypercalcaemia with highly elevated levels of calcitriol, which can cause massive nephrocalcinosis and subsequent loss of kidney function [16].

How long should patients be on dual antiplatelet therapy?

The use of dual anti-platelet therapy is critically important for the prevention of coronary stent thrombosis (2). Current clinical guidelines recommend at least 6- to 12-month treatment after DES implantation, but a longer duration of dual antiplatelet therapy (DAPT) may be beneficial.

Is clopidogrel safer than aspirin?

For the safety profile, clopidogrel group had a 2.60-fold risk (95% CI = 2.82–3.70) of gastrointestinal (GI) bleeding than aspirin group. However, the risks of intracerebral haemorrhage and death were not different between groups before and after matching.

How long should I take clopidogrel after a TIA?

Based on the results of the CHANCE trial, the American Heart Association/American Stroke Association recommends clopidogrel and aspirin for 21 days starting in the first 24 hours after a minor stroke or TIA.

Can I take doxycycline for 14 days?

For most infections, doxycycline is taken once or twice daily for 7 to 14 days. For adult infections, the usual dose of oral doxycycline is 200 mg on the first day of treatment (100 mg every 12 hours) followed by a dose of 100 to 200 mg/day as a single dose or divided and administered twice daily.

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