What does a high B. pertussis IgG AB mean?
Positive (> or =100 IU/mL): IgG antibodies to pertussis toxin (PT) detected. Results suggest recent infection with or recent vaccination against Bordetella pertussis.
Is Bordetella pertussis positive or negative?
Bordetella pertussis is a small (approximately 0.8 μm by 0.4 μm), rod-shaped, coccoid, or ovoid Gram-negative bacterium that is encapsulated and does not produce spores.
How is Bordetella pertussis diagnosed?
Clinicians commonly use several types of laboratory tests to diagnose Bordetella pertussis. Scientists consider culture the gold standard because it is the only 100% specific method for identification. Other tests that can be performed include polymerase chain reaction (PCR) and serology.
How long does it take for pertussis test results?
With PCR, the most rapid test, ideally collect the specimen during the first 3 weeks of illness. However, PCR may provide accurate results for up to 4 weeks. Culture has better specificity, but takes up to 7 days to obtain results.
What does a positive pertussis test mean?
A positive PCR test means that it is likely that the person has pertussis. However, the PCR test may also be positive with other Bordetella species. A negative PCR test means that it is less likely that the person has pertussis but does not rule it out.
How long does pertussis IgG stay positive?
With blood testing, pertussis IgG antibodies will be present in those who have been vaccinated or have had a past infection. IgM and IgA antibodies may indicate recent vaccination or infection and will only be present for a short period of time (2-3 months).
Is Bordetella pertussis Gram-negative?
SYNONYM OR CROSS REFERENCE: Originally named Haemophilus pertussis F 1, Whooping cough 2. CHARACTERISTICS: Bordetella pertussis are small, gram-negative, encapsulated, non-motile, coccobacilli with outer pili. They are generally about 0.5-1.0 µm in size 3- 5.
What type of infection is Bordetella pertussis?
Pertussis, a respiratory illness commonly known as whooping cough, is a very contagious disease caused by a type of bacteria called Bordetella pertussis. These bacteria attach to the cilia (tiny, hair-like extensions) that line part of the upper respiratory system.
What is a confirmed diagnosis?
A final diagnosis that is made after getting the results of tests, such as blood tests and biopsies, that are done to find out if a certain disease or condition is present.
Is Bordetella pertussis a virus or bacteria?
Pertussis is also known as whooping cough. It is a highly infectious bacterial disease involving the respiratory tract. It is caused by a bacterium (Bordetella pertussis or Bordetella parapertussis ) that is found in the mouth, nose and throat of an infected person.
What are the symptoms of Bordetella pertussis?
After 1 to 2 weeks and as the disease progresses, the traditional symptoms of pertussis may appear and include:
- Paroxysms (fits) of many, rapid coughs followed by a high-pitched “whoop” sound.
- Vomiting (throwing up) during or after coughing fits.
- Exhaustion (very tired) after coughing fits.
What is a PCR test for pertussis?
Polymerase chain reaction (PCR) is an important tool for timely diagnosis of pertussis and is increasingly available to clinicians. PCR is a molecular technique used to detect DNA sequences of the Bordetella pertussis bacterium and unlike culture, does not require viable (live) bacteria present in the specimen.
Does pertussis show up in blood work?
Blood test for pertussis antibodies, IgA, IgG, IgM – these blood tests detect antibodies produced by the body’s immune response to a pertussis infection. Antibody testing is not useful to determine if a person has had a recent pertussis infection.
Can adults catch pertussis?
Whooping cough, or pertussis, is a highly contagious condition. This infection is most common in infants, but people of all ages can contract it. Whooping cough symptoms tend to be less severe in adults than in children.